GENICULAR ARTERY EMBOLIZATION (GAE)
Genicular artery embolization (GAE) is a minimally invasive procedure designed to reduce knee pain associated with osteoarthritis (OA). Our goal is to provide you with comprehensive information to help you understand the process, benefits, risks, and recovery period associated with GAE.
Contact AVC to see if you are a candidate for Genicular Artery Embolization (GAE).
Overview of Genicular Artery Embolization (GAE)
Genicular Artery Embolization (GAE) is a minimally invasive, image-guided procedure designed to treat chronic knee pain, particularly osteoarthritis-related pain. By targeting and reducing inflammation in the knee joint, GAE provides a non-surgical alternative for individuals who may not benefit from or are not candidates for surgical interventions like total knee replacement.
During the procedure, an interventional radiologist uses fluoroscopic imaging to navigate a catheter through the vascular system to the knee’s genicular arteries. Tiny particles, often made of medical-grade microspheres, are then injected into these arteries to reduce blood flow to inflamed areas of the knee. This helps decrease inflammation, pain, and associated symptoms.
Benefits of Genicular Artery Embolization (GAE)
- Non-Surgical and Minimally Invasive
- GAE is performed through a small incision, avoiding the risks and recovery time associated with traditional knee surgeries.
- Pain Relief
- Patients often experience significant pain reduction within days to weeks after the procedure, improving quality of life.
- Reduced Recovery Time
- Since it is a minimally invasive outpatient procedure, recovery is quicker compared to surgical alternatives, allowing patients to resume daily activities sooner.
- Low Risk of Complications
- The targeted nature of the embolization minimizes the impact on surrounding tissues and reduces the risk of complications compared to more invasive treatments.
- Option for Patients Unsuitable for Surgery
- GAE is an excellent alternative for individuals who cannot undergo surgery due to medical conditions, age, or personal preference.
- Delay or Avoidance of Surgery
- For some patients, GAE can help manage symptoms effectively enough to delay or eliminate the need for knee replacement surgery.
- Preservation of Knee Anatomy
- Unlike joint replacement, GAE does not alter the natural structure of the knee, preserving its anatomy and movement.
- Repeatable Procedure
- If symptoms recur, the procedure can be repeated, providing long-term management for chronic knee pain.
- Broad Applicability
- GAE is effective for treating pain related to moderate to severe osteoarthritis, as well as other conditions that cause chronic knee inflammation.
- Enhanced Quality of Life
- With reduced pain and improved mobility, patients often report a higher overall quality of life post-procedure.
GAE is a promising advancement in interventional radiology and pain management, offering a less invasive yet effective solution for chronic knee pain.
The Thrombectomy Procedure
Thrombectomy is a minimally invasive surgical procedure used to remove blood clots from arteries, particularly in the brain, in patients experiencing acute ischemic strokes. Here is a step-by-step guide to the thrombectomy procedure:
1. Patient Evaluation and Preparation:
- The patient is evaluated to determine if they meet the criteria for thrombectomy, which typically includes a confirmed diagnosis of acute ischemic stroke and the presence of a large vessel occlusion.
- The patient’s medical history, including any allergies, medications, and previous surgeries, is reviewed.
- The patient’s vital signs are monitored, and blood tests may be conducted.
2. Anesthesia:
- The patient is usually given local anesthesia at the site where the catheter will be inserted (e.g., groin) to numb the area. In some cases, general anesthesia may be used.
3. Accessing the Artery:
- A small incision is made in the skin at the site where the catheter will be inserted.
- A catheter is then inserted into a large artery, typically in the groin (femoral artery), and guided through the arterial system using fluoroscopy (real-time X-ray imaging).
4. Advancing the Catheter:
- The catheter is advanced through the arterial system, typically up into the carotid artery or one of its branches, depending on the location of the clot.
5. Clot Retrieval:
- Once the catheter reaches the site of the clot, a specialized device, such as a stent retriever or aspiration catheter, is used to physically remove the clot.
- Stent retrievers are designed to ensnare the clot and allow it to be removed intact, while aspiration catheters use suction to remove the clot.
- The device is carefully maneuvered to engage with the clot without damaging the artery walls.
6. Clot Removal:
- Once the clot is captured by the device, it is slowly withdrawn from the artery, taking care to prevent fragmentation of the clot, which could lead to distal embolization (clot traveling to other parts of the brain).
7. Confirming Revascularization:
- After the clot is removed, angiography (X-ray imaging of blood vessels) is performed to confirm that blood flow has been restored to the affected area of the brain.
8. Closure of the Incision Site:
- After the procedure is completed, the catheter is removed, and the incision site is typically closed using sutures or a closure device.
- Pressure may be applied to the site to prevent bleeding.
9. Post-Procedure Care:
- The patient is closely monitored in a specialized stroke unit or intensive care unit.
- Neurological assessments are performed regularly to monitor for any signs of improvement or complications.
10. Recovery and Rehabilitation:
- Depending on the extent of the stroke and the patient’s overall health, rehabilitation may be necessary to help regain lost function and improve quality of life.
Risks and Complications
While thrombectomy has been shown to be highly effective in certain patient populations, there are still challenges and considerations that need to be addressed. One of the primary challenges is the need for timely access to thrombectomy, as the procedure is most effective when performed as soon as possible after symptom onset. This requires a well-coordinated system of care, including efficient transport protocols and access to specialized stroke centers.
FAQS
What is Genicular Artery Embolization (GAE)?
GAE is a procedure that targets the genicular arteries, which supply blood to the knee joint. By blocking these arteries, the procedure reduces inflammation and pain caused by osteoarthritis. It is performed by a specialist called an interventional radiologist, using a catheter and small particles to block the blood flow.
How is GAE performed?
This outpatient procedure is performed under local anesthesia and mild sedation. The interventional radiologist inserts a catheter into an artery in your femoral artery or wrist, which is then guided to the genicular arteries in your knee. Tiny particles are then injected to block the blood flow to the inflamed areas, reducing inflammation and pain. The procedure takes about 60 minutes and you can plan to go home the same day.
What are the benefits of GAE?
GAE is a minimally invasive procedure, meaning it requires only a small incision, reducing the risk of infection and promoting quicker recovery. It can significantly reduce or eliminate pain and improve knee function without the need for knee surgery.
Is there harm in shutting off blood flow to the knee?
No, the procedure targets abnormal blood vessels that cause increased inflammation and pain. Shutting these abnormal blood vessels results in decreased inflammation and pain while preserving blood flow to the rest of the knee.
What are the risks of GAE?
As with any medical procedure, GAE has minor risks. These may include bleeding or infection at the catheter insertion site, temporary skin changes, and non-target embolization. However, these risks are relatively low, and your provider will discuss them with you in detail prior to the procedure.
What is the recovery process? Are there activity restrictions?
You may experience some knee discomfort or swelling for a few days after the procedure, which can be managed with over-the-counter pain medication. You should be able to return to normal activities within a week, although you should avoid strenuous exercise for a few weeks.
How effective is GAE?
Studies have shown that GAE can significantly reduce knee pain caused by osteoarthritis for more than 2 years. However, as with any medical procedure, individual results may vary. Your doctor will discuss with you whether GAE is the best treatment option for your specific condition.
Can I get a knee replacement after GAE?
Yes, studies have demonstrated no complications with receiving a knee replacement after GAE.